Lurie R, Danziger Y, Kaplan Y, Sulkes J, Abramson E, Mimouni M
Department of Dermatology at Beilinson Medical Center, Petah Tiqva, Israel.
Cutis. 1996 Mar;57(3):151-6.
The hair of seventeen girls aged 13 to 19 years with anorexia nervosa (AN) was studied and compared with the hair of fifteen healthy girls aged 13 to 18 years with no complaints of hair loss but with similar habits of hairstyling and care. Light microscopic examination of the hair revealed no defect in the control group. In the AN group, fourteen patients (82.3 percent) had pili torti, an acquired hair shaft defect that has not yet been described in association with this disease. We estimate that the hair defect was due to malnutrition combined with ingestion of exaggerated amounts of yellow vegetables and vitamin supplements, causing a significant increase in levels of serum carotene, retinyl esters, retinol, and retinoic acid. We suggest a possible link between excess vitamin A and pili torti in patients with AN.
对17名年龄在13至19岁之间患有神经性厌食症（AN）的女孩的头发进行了研究，并与15名年龄在13至18岁之间、无脱发主诉但发型和护理习惯相似的健康女孩的头发进行了比较。对头发的光学显微镜检查显示，对照组没有缺陷。在AN组中，14名患者（82.3%）有扭曲发，这是一种获得性毛干缺陷，此前尚未发现与该疾病有关。我们估计，头发缺陷是由于营养不良，再加上摄入了过量的黄色蔬菜和维生素补充剂，导致血清胡萝卜素、视黄酯、视黄醇和视黄酸水平显著升高。我们认为，AN患者体内维生素A过量与扭曲发之间可能存在联系。
