El'skiĭ V N
Vopr Med Khim. 1977 May-Jun(3):365-9.
Content of serotonin was increased approximately 3-fold in brain, 8-fold in liver tissue, 15-16-fold in kidney and heart, as compared with control, after traumatic shock caused by crushing of rat soft tissues. At the same time content of serotonin was decreased in lungs by 40% and in intestine -- by 80%. The MAO activity was altered in all the tissues studied. The alterations followed a similar pattern in all the cases: short-term increase, decrease, restoration after completing the compression and persistent decrease in decompressional period.
与对照组相比,大鼠软组织挤压所致创伤性休克后,大脑中血清素含量增加约3倍,肝组织中增加8倍,肾脏和心脏中增加15 - 16倍。与此同时,肺中血清素含量降低40%,肠道中降低80%。所研究的所有组织中的单胺氧化酶(MAO)活性均发生改变。所有情况下的变化模式相似:短期升高、降低,压迫结束后恢复,减压期持续降低。