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两项流行病学研究中的精神药物与失眠主诉

Psychotropic medication and insomnia complaints in two epidemiological studies.

作者信息

Ohayon M M, Caulet M

机构信息

Centre de recherche Philippe Pinel de Montréal, Quebec.

出版信息

Can J Psychiatry. 1996 Sep;41(7):457-64. doi: 10.1177/070674379604100711.

Abstract

OBJECTIVE

This study compared prescribed psychotropic medication patterns for reported sleep disorders in French and Quebec samples.

METHOD

The first study was undertaken in France (N = 5622) and the second in the metropolitan area of Montreal (N = 1722). Lay interviewers used a specialized knowledge-based system for the purpose of evaluating sleep disorders by telephone.

RESULTS

Results showed similar prevalence of insomnia complaints in both samples (20.1% and 17.8%, respectively). A higher level of psychotropic consumption was found in France (11.7% [95% confidence interval (CI), 10.9 to 12.5]) compared with Quebec, however, where consumption was less than half the French rate (5.5% [95% CI, 4.4 to 6.6]). Both studies identified females and the elderly as the primary consumers of these drugs. For approximately two-thirds of both samples, sleep-promoting medications were prescribed for a year or longer, revealing a chronicity of the consumption. Approximately 4 out of 5 prescriptions for sleeping medications were ordered by general practitioners in both samples.

CONCLUSION

These findings clearly show a higher prevalence of psychotropic drug use in the French compared with the Quebec population. The patterns of consumption and prescription, however, are quite similar in both studies.

摘要

目的

本研究比较了法国和魁北克样本中针对报告的睡眠障碍所开具的精神药物用药模式。

方法

第一项研究在法国开展(N = 5622),第二项研究在蒙特利尔市区开展(N = 1722)。外行人访谈员使用一个基于专业知识的系统通过电话评估睡眠障碍。

结果

结果显示两个样本中失眠主诉的患病率相似(分别为20.1%和17.8%)。然而,法国的精神药物消费水平更高(11.7% [95%置信区间(CI),10.9至12.5]),而魁北克的消费水平不到法国的一半(5.5% [95% CI,4.4至6.6])。两项研究均确定女性和老年人是这些药物的主要消费者。在两个样本中,约三分之二的促眠药物处方开具时长为一年或更长时间,这表明用药具有长期性。在两个样本中约五分之四的睡眠药物处方是由全科医生开具的。

结论

这些发现清楚地表明,与魁北克人群相比,法国使用精神药物的患病率更高。然而,两项研究中的消费和处方模式相当相似。

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