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[法国人口中的老年人、睡眠习惯与精神药物使用情况]

[The elderly, sleep habits and use of psychotropic drugs by the French population].

作者信息

Ohayon M, Caulet M, Lemoine P

机构信息

Psychiatre des Hôpitaux, Directeur du Centre de Recherche Philippe Pinel de Montréal, Québec, Canada.

出版信息

Encephale. 1996 Sep-Oct;22(5):337-50.

PMID:9035990
Abstract

The aging population in western countries and the increase in longevity make the problem of recognition and treatment of sleep disorders more acute in the elderly population. The risk of evolution of sleep disorders in the elderly leads to a greater weakness of their physical health, a greater dependence on their environment, and finally to more frequent recourse to institutionalization. We investigated sleep habits, sleep disorders and psychiatric diagnoses, physical illnesses and psychotropic drug consumption in a representative sample of the general population of France. Interviews were performed over the telephone by lay interviews using the Eval Knowledge Based System, a computerized system that guides the interviewer through the interview process, 6966 subjects were contacted, and 5622 interviews (80.8% of the potential sample) were completed. The sample was divided into four age groups: 15 to 44 years old (56.4%); 45 to 64 years old (25.6%); 65 to 74 years old (10.8%) and 75 years old or more (7.2%). Earlier bedtime, long sleep latency, spending more time in bed with a reduction of nocturnal sleep time, nocturnal awakenings and daytime naps were found more frequently in "young old" (65 to 75 years old) and "old old" subjects (75 years old or more). Daytime naps and spending more time in bed with a reduction of nocturnal sleep time also distinguished "old old" subjects from "young old" subjects. About half of "old old" subjects who complained about their sleep did not get a diagnosis of sleep disorder, nor psychiatric disorder (52.4%). An insomnia diagnosis was given in 14% of cases (mostly primary insomnia-6.7%) and a psychiatric diagnosis in 33.4% of cases (mostly anxiety diagnoses-28.2%). The rate of psychotropic drug consumption was 11.7% (95% Cl: 10.9% to 12.5%) for the entire sample. This consumption dramatically increased with age: 4.8% between 15 to 44 years old; 15.6% between 45 to 64 years old; 24.3% in "young old" subjects and 32.8% in "old old" subjects. Psychotropic drug consumption was distributed as follows: 6.4% of the sample used anxiolytic, 2.7% hypnotic, 1.5% antidepressant and 0.9% hypnotic and anxiolytic together. The chronic use (at least one year) of hypnotic or anxiolytic drugs was frequent in "old old" subjects (92.6% and 80.2%, respectively) and "young old" subjects (74% and 78% respectively). The assessment of sleep by the physician should be made part of the routine clinical examination of older subjects. Review of the etiology of insomnia complaints is crucial in the choice of treatment. The reflex of psychotropic prescription in case of poor sleep is neither sufficient nor desirable, especially because of the risk of chronic use of the prescription. These data underline the importance of educating physicians about consequences of long-term utilization of these drugs and on the need for sleep hygiene measures as alternative solutions for treating insomnia complaints.

摘要

西方国家人口老龄化和寿命延长使得老年人睡眠障碍的识别与治疗问题愈发尖锐。老年人睡眠障碍的发展风险导致其身体健康更虚弱,对环境的依赖性更强,最终使得机构收容更为频繁。我们对法国普通人群的一个代表性样本的睡眠习惯、睡眠障碍、精神疾病诊断、身体疾病及精神药物消费情况进行了调查。通过使用Eval知识系统,由非专业访谈人员通过电话进行访谈,该系统是一个计算机化系统,可在访谈过程中引导访谈人员。共联系了6966名受试者,完成了5622次访谈(占潜在样本的80.8%)。样本分为四个年龄组:15至44岁(56.4%);45至64岁(25.6%);65至74岁(10.8%)以及75岁及以上(7.2%)。在“年轻老人”(65至75岁)和“高龄老人”组(75岁及以上)中,较早的就寝时间、较长的入睡潜伏期、在床上时间增加但夜间睡眠时间减少、夜间觉醒及日间小睡更为常见。日间小睡以及在床上时间增加但夜间睡眠时间减少也使“高龄老人”组与“年轻老人”组有所区别。约一半抱怨睡眠问题的“高龄老人”既未被诊断出睡眠障碍,也未被诊断出精神疾病(52.4%)。14%的病例被诊断为失眠(大多为原发性失眠——6.7%),33.4%的病例被诊断为精神疾病(大多为焦虑症——28.2%)。整个样本的精神药物消费率为11.7%(95%置信区间:10.9%至12.5%)。这种消费随年龄显著增加:15至44岁为4.8%;45至64岁为15.6%;“年轻老人”组为24.3%,“高龄老人”组为32.8%。精神药物消费分布如下:6.4%的样本使用抗焦虑药,2.7%使用催眠药,1.5%使用抗抑郁药,0.9%同时使用催眠药和抗焦虑药。“高龄老人”组(分别为92.6%和80.2%)和“年轻老人”组(分别为74%和78%)中,长期(至少一年)使用催眠药或抗焦虑药的情况较为常见。医生对睡眠的评估应成为老年受试者常规临床检查的一部分。对失眠主诉病因的审查对于治疗选择至关重要。睡眠不佳时开具精神药物的做法既不充分也不可取,尤其是考虑到长期使用该处方的风险。这些数据凸显了对医生进行教育的重要性,使其了解这些药物长期使用的后果以及采取睡眠卫生措施作为治疗失眠主诉替代解决方案的必要性。

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