胆管结扎或ANIT诱导胆汁淤积大鼠体内及体外的己巴比妥氧化作用（作者译）
[Hexobarbital-oxidation in vivo and in vitro in rats with bile duct ligation or ANIT-cholestasis (author's transl)].
作者信息
Brachtel D, Gallenkamp H, Richter E
出版信息
Z Gastroenterol. 1977 Jun;15(6):378-80.
PMID:888487
Abstract
Pharmacokinetics of hexobarbital in rats is not influenced by ligature of the common bile duct or by ANIT-cholestasis. Additional in vitro experiments with isolated liver microsomes show only slight changes of hexobarbital metabolism.
摘要
己巴比妥在大鼠体内的药代动力学不受胆总管结扎或ANIT诱导的胆汁淤积的影响。用分离的肝微粒体进行的额外体外实验表明己巴比妥代谢仅有轻微变化。
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