Fields S J, Vainder M, Livshits G, Merlob P, Sirotta L
Tel Aviv University, Ramat Aviv, Israel.
Ann Hum Biol. 1996 Sep-Oct;23(5):353-62. doi: 10.1080/03014469600004602.
The purpose of the present study was to examine the relationship between severe pre-eclampsia/eclampsia (toxaemia) and obesity. We collected sociodemographic, anthropometric, medical and pregnancy outcome data from the hospital records of 248 Israeli women diagnosed with either pregnancy-induced or chronic hypertension, and compared these data to a control group of 236 women. Univariate analysis showed that while there exists a statistically significant positive association between obesity and hypertension (both pregnancy-induced and chronic) obesity presents no added risk to the development of toxaemia. Furthermore, we found a significant decrease in the rate of obesity among primigravid versus multigravid mothers with toxaemia superimposed on pregnancy-induced hypertension. On the other hand, primigravid mothers with PIH were at an increased risk of developing toxaemia as compared to multigravid women. These results suggest that obesity is not a significant factor in the development of toxaemia.
本研究的目的是检验重度子痫前期/子痫（毒血症）与肥胖之间的关系。我们从248名被诊断为妊娠高血压或慢性高血压的以色列女性的医院记录中收集了社会人口统计学、人体测量学、医学和妊娠结局数据，并将这些数据与236名女性的对照组进行比较。单因素分析表明，虽然肥胖与高血压（包括妊娠高血压和慢性高血压）之间存在统计学上显著的正相关，但肥胖对毒血症的发生没有额外风险。此外，我们发现，与多胎妊娠母亲相比，初产妇中肥胖率显著降低，这些初产妇的子痫前期合并妊娠高血压。另一方面，与多胎妊娠女性相比，患有妊娠高血压的初产妇发生毒血症的风险增加。这些结果表明，肥胖不是毒血症发生的重要因素。
