Tos M, Morgensen C
Acta Otolaryngol. 1977 May-Jun;83(5-6):498-504. doi: 10.3109/00016487709128878.
The entire nasal mucosa from a patient with nasal allergy and hay fever was studied by the whole mount method, and the density of submucous glands was determined. Their density was essentially greater than in normal noses in all parts of the nose, especially on the conchae. This finding indicates that new-abnormal-glands form in the course of the disease, glands which also differ morphologically from the normally occurring glands. As this greatly increases the secretory capacity of the mucous membrane, there is a patho-anatomical basis for assuming that the nasal secretion in allergy is formed exclusively by the existing glands. Other sources of nasal secretion, such as exudation and transudation under normal conditions and in allergy, as well as the mode and causes of gland formation, are discussed.
采用整装法对一名患有鼻过敏和花粉热患者的整个鼻黏膜进行了研究,并测定了黏膜下腺的密度。在鼻子的所有部位,尤其是鼻甲处,其密度基本上都高于正常鼻子。这一发现表明,在疾病过程中会形成新的异常腺体,这些腺体在形态上也与正常存在的腺体不同。由于这极大地增加了黏膜的分泌能力,因此有病理解剖学依据认为,过敏时的鼻分泌物完全由现有腺体形成。还讨论了鼻分泌物的其他来源,如正常情况和过敏时的渗出和滤过,以及腺体形成的方式和原因。