Molecular mechanisms in the regulation of renal proximal tubular Na/phosphate cotransport.
作者信息
Murer H, Lötscher M, Kaissling B, Biber J
机构信息
Physiologisches Institut, Zürich, Schweiz.
出版信息
Kidney Blood Press Res. 1996;19(3-4):151-4. doi: 10.1159/000174063.
PMID:8887250
Abstract
Renal proximal tubular Na/phosphate cotransport is the key target in the control of renal phosphate handling. Using molecular tools for the type II Na/phosphate cotransporter, it could be documented that altered brush border membrane phosphate transport reflects a state of altered brush border expression of the specific transporter molecule. This alteration is either the consequence of specific membrane insertion/retrieval processes and/or reflects states of altered synthesisdegradation of the transporter.
摘要
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