Ioannides K G, Karamanis D T, Stamoulis K C, Mertzimekis T J, Mantzios A S, Nicolaou E, Pappas C P
Nuclear Physics Laboratory, University of Ioannina, Greece.
Health Phys. 1996 Nov;71(5):713-8. doi: 10.1097/00004032-199611000-00011.
The effectiveness of Prussian Blue in reducing the radiocesium contamination in ovine tissues was investigated. Five ewes were fed 137Cs-contaminated wheat for 30 d. When the 137Cs concentration in milk had reached equilibrium, one animal, serving as the control, was slaughtered and the activity in its tissues was measured. Two ewes were offered daily 1 g of Prussian Blue labeled with 59Fe in the Fe(III) position, outside the complex anion. One week after the administration of Prussian Blue, these animals were slaughtered, 1 wk apart, and the level of 137Cs in their tissues was measured. Comparing the concentration of 137Cs in the blood and tissues of the Prussian Blue treated animals to the corresponding concentrations measured in the control, a considerable reduction in the radiocesium activity concentration is observed. However, 137Cs concentrations are maintained at non-zero (about 20%) values in the first 2 wk after the administration of Prussian Blue. This observation can be attributed to the fact that most of 137Cs binds to Prussian Blue in the animals' digestive tracts and the measured activity concentrations follow the elimination of cesium from tissues. Using a two-compartment mathematical model, we can predict the level of 137Cs in tissue, following the administration of Prussian Blue. Labeling Prussian Blue in the Fe(III)-position resulted in the measurement of a (2.4 +/- 0.02) % retention of Fe(III) in sheep.
研究了普鲁士蓝在降低绵羊组织中放射性铯污染方面的有效性。五只母羊喂食受137Cs污染的小麦30天。当牛奶中的137Cs浓度达到平衡时，宰杀一只作为对照的动物，并测量其组织中的放射性活度。给两只母羊每天投喂1克在络合阴离子之外的Fe(III)位置用59Fe标记的普鲁士蓝。在投喂普鲁士蓝一周后，分别间隔1周宰杀这些动物，并测量其组织中的137Cs水平。将接受普鲁士蓝处理的动物血液和组织中的137Cs浓度与对照中测量的相应浓度进行比较，观察到放射性铯活度浓度有显著降低。然而，在投喂普鲁士蓝后的前2周，137Cs浓度维持在非零（约20%）值。这一观察结果可归因于大部分137Cs在动物消化道中与普鲁士蓝结合，且测量的活度浓度随铯从组织中的消除而变化。使用双室数学模型，我们可以预测投喂普鲁士蓝后组织中137Cs的水平。在Fe(III)位置标记普鲁士蓝导致在绵羊中测量到Fe(III)的保留率为(2.4±0.02)%。
