Min Y G, Kim Y K, Kim H S
Department of Otorhinolaryngology, College of Medicine, Seoul National University, Korea.
Clin Otolaryngol Allied Sci. 1996 Aug;21(4):339-42. doi: 10.1111/j.1365-2273.1996.tb01083.x.
This study attempts to evaluate the use of auricular cartilage for the treatment of nasal septal defects. A defect was made in the nasal septal cartilage in five rabbits and auricular cartilage grafted into the defect. The cartilage was microscopically examined 4 weeks later. The implanted cartilage was completely covered by ciliated columnar epithelium with minimal scar formation. Proliferation of the implanted cartilage and scattered ossification were observed. Seventeen patients with a nasal septal defect were treated by auricular cartilage implantation from April 1987 to through June 1992. Fifteen patients (88%) had relief of symptoms and showed complete closure of the defect with a follow-up period of 2 years. The results of this study suggest that auricular cartilage may be of value in the repair of a nasal septal defect.
本研究旨在评估耳廓软骨用于治疗鼻中隔缺损的效果。在五只兔子的鼻中隔软骨上制造缺损，并将耳廓软骨移植到缺损处。4周后对软骨进行显微镜检查。植入的软骨完全被纤毛柱状上皮覆盖，瘢痕形成极少。观察到植入软骨有增生及散在骨化现象。1987年4月至1992年6月，17例鼻中隔缺损患者接受了耳廓软骨植入治疗。15例患者（88%）症状缓解，随访2年时缺损完全闭合。本研究结果提示，耳廓软骨在鼻中隔缺损修复中可能具有价值。
