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星形诺卡菌在小鼠肺和脑中的差异结合表明诺卡菌表面存在多种配体。

Differential binding of Nocardia asteroides in the murine lung and brain suggests multiple ligands on the nocardial surface.

作者信息

Beaman B L

机构信息

Department of Medical Microbiology and Immunology, University of California School of Medicine, Davis 95616, USA.

出版信息

Infect Immun. 1996 Nov;64(11):4859-62. doi: 10.1128/iai.64.11.4859-4862.1996.

Abstract

The adherence of Nocardia asteroides in the murine brain and lungs was determined. Virulent strains had increased adherence in the brain and lungs, whereas less virulent strains bound in either the brain or lungs. Nocardiae that attached apically penetrated host cells. Multiple receptors on the nocardial surface may be involved in this differential attachment and penetration.

摘要

测定了星形诺卡菌在小鼠脑和肺中的黏附情况。强毒株在脑和肺中的黏附增加,而弱毒株仅在脑或肺中黏附。顶端黏附的诺卡菌会穿透宿主细胞。诺卡菌表面的多种受体可能参与了这种差异黏附和穿透过程。

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