De Renzi E, Cavalleri F, Facchini S
Neurology Department, University of Modena, Italy.
J Neurol Neurosurg Psychiatry. 1996 Oct;61(4):396-400. doi: 10.1136/jnnp.61.4.396.
To investigate the incidence, anatomical correlates, and clinical features of imitation and utilisation behaviour, which are thought by Lhermitte and coworkers to represent a reliable and frequent index of frontal lobe disease.
78 patients with hemispheric local lesions were tested in two separate sessions, in which their reactions to a series of gestures performed by the examiner and to the presentation of a set of objects were recorded. The patients were stratified into a frontal (n = 52) and a non-frontal group (n = 26) on the basis of their CT data.
Imitation behaviour was present in 39% of the frontal patients and was mainly associated with medial and lateral lesions, at odds with the claim of Lhermitte et al that it is a constant accompaniment of lower, mediobasal lesions. In the non-frontal group it was found in three patients, all with damage to the deep nuclei region. Utilisation behaviour was a much rarer phenomenon, present in only two patients, both of whom had frontal damage. Neither imitation behaviour nor utilisation behaviour were found in patients with retrorolandic cortical lesions.
研究模仿和运用行为的发生率、解剖学关联及临床特征,Lhermitte及其同事认为这些行为是额叶疾病的可靠且常见指标。
78例半球局部病变患者分两次接受测试,记录他们对检查者做出的一系列手势以及一组物品呈现的反应。根据CT数据将患者分为额叶组(n = 52)和非额叶组(n = 26)。
39%的额叶患者存在模仿行为,主要与内侧和外侧病变相关,这与Lhermitte等人认为其是下部、内侧基底病变的持续伴随症状的观点相悖。在非额叶组中,3例患者存在模仿行为,均为深部核团区域受损。运用行为是一种更为罕见的现象,仅在2例额叶受损患者中出现。顶叶皮质病变患者未发现模仿行为和运用行为。