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胸锁关节骨肥厚:胸骨、锁骨和上肋骨疼痛性肿胀。两例新病例报告。

Sternocostoclavicular hyperostosis: painful swelling of the sternum, clavicles, and upper ribs. Report of two new cases.

作者信息

Köhler H, Uehlinger E, Kutzner J, West T B

出版信息

Ann Intern Med. 1977 Aug;87(2):192-7. doi: 10.7326/0003-4819-87-2-192.

Abstract

Five patients had persistent, pulling pain in the sternum, clavicles, and upper ribs that was exacerbated by cold and dampness. Clublike, symmetrical enlargement of the clavicles was seen and, in two patients, venous congestion of the upper half of the body. All patients had a constantly elevated erythrocyte sedimentation rate. Radiologically there was symmetrical hyperostosis of the sternal and middle portions of the clavicles, synostosis of the sternoclavicular joints, a widened and thickened sternum, and varying degrees of involvement of the upper ribs. X-ray findings did not change over several years. Phlebography showed bilateral subclavian vein occlusion in three patients and unilateral occlusion in one. Biopsies of the clavicles showed a characteristic hyperostotic sclerosis of the spongiosa. The cause of this sternocostoclavicular hyperostosis is unknown, but clinical, radiologic, and histologic findings indicate that it may represent a distinct, hitherto undescribed entity.

摘要

5例患者胸骨、锁骨和上肋骨持续出现牵拉性疼痛,遇冷受潮时加重。可见锁骨呈杵状、对称性增粗,2例患者出现上半身静脉充血。所有患者红细胞沉降率持续升高。放射学检查显示,锁骨胸骨段和中段对称性骨质增生、胸锁关节骨性融合、胸骨增宽增厚,上肋骨受累程度不一。数年来X线表现无变化。静脉造影显示3例患者双侧锁骨下静脉闭塞,1例单侧闭塞。锁骨活检显示松质骨有特征性的骨质增生性硬化。这种胸肋锁骨骨质增生的病因尚不清楚,但临床、放射学和组织学检查结果表明,它可能是一种独特的、迄今尚未描述的疾病。

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