呼肠孤病毒非结构蛋白sigma1NS可被小鼠细胞毒性T淋巴细胞识别。
The reovirus nonstructural protein sigma1NS is recognized by murine cytotoxic T lymphocytes.
作者信息
Hoffman L M, Hogan K T, Cashdollar L W
机构信息
Department of Microbiology, Medical College of Wisconsin, Milwaukee 53226, USA.
出版信息
J Virol. 1996 Nov;70(11):8160-4. doi: 10.1128/JVI.70.11.8160-8164.1996.
Abstract
The cytotoxic T-lymphocyte (CTL) response in reovirus-infected C3H mice was investigated by using reovirus-vaccinia virus recombinants. Results of cytotoxicity assays indicated that the nonstructural protein sigma1NS elicited a significant CTL response. Experiments with sigma1NS-specific CTL lines showed that both strain-specific and cross-reactive epitopes exist in the sigma1NS protein.
摘要
利用呼肠孤病毒-痘苗病毒重组体研究了呼肠孤病毒感染的C3H小鼠中的细胞毒性T淋巴细胞（CTL）反应。细胞毒性试验结果表明，非结构蛋白sigma1NS引发了显著的CTL反应。对sigma1NS特异性CTL系的实验表明，sigma1NS蛋白中存在菌株特异性和交叉反应性表位。
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本文引用的文献
1
Protein sigma 1 is the reovirus cell attachment protein.蛋白质σ1是呼肠孤病毒的细胞附着蛋白。
Virology. 1981 Jan 15;108(1):156-63. doi: 10.1016/0042-6822(81)90535-3.
2
Absolute linkage of virulence and central nervous system cell tropism of reoviruses to viral hemagglutinin.呼肠孤病毒的毒力和中枢神经系统细胞嗜性与病毒血凝素的绝对关联。
J Infect Dis. 1980 May;141(5):609-16. doi: 10.1093/infdis/141.5.609.
3
Type-specific reovirus antiserum blocks the cytotoxic T-cell-target cell interaction: evidence for the association of the viral hemagglutinin of a nonenveloped virus with the cell surface.型特异性呼肠孤病毒抗血清阻断细胞毒性T细胞与靶细胞的相互作用：无包膜病毒的病毒血凝素与细胞表面相关的证据。
Infect Immun. 1981 Feb;31(2):646-9. doi: 10.1128/iai.31.2.646-649.1981.
4
Molecular cloning of the complete genome of reovirus serotype 3.呼肠孤病毒3型全基因组的分子克隆
Virology. 1984 Feb;133(1):191-6. doi: 10.1016/0042-6822(84)90438-0.
5
6
Mapping of the vaccinia virus thymidine kinase gene by marker rescue and by cell-free translation of selected mRNA.通过标记拯救和对选定信使核糖核酸的无细胞翻译来定位牛痘病毒胸苷激酶基因。
Proc Natl Acad Sci U S A. 1982 Feb;79(4):1210-4. doi: 10.1073/pnas.79.4.1210.
7
Polypeptide components of virions, top component and cores of reovirus type 3.呼肠孤病毒3型病毒粒子的多肽成分、顶部成分和核心
Virology. 1969 Dec;39(4):791-810. doi: 10.1016/0042-6822(69)90017-8.
8
Biosynthesis of reovirus-specified polypeptides: the reovirus s1 mRNA encodes two primary translation products.呼肠孤病毒特异性多肽的生物合成：呼肠孤病毒s1 mRNA编码两种初级翻译产物。
Virology. 1985 May;143(1):63-74. doi: 10.1016/0042-6822(85)90097-2.
9
Identification of a new polypeptide coded by reovirus gene S1.呼肠孤病毒基因S1编码的一种新多肽的鉴定
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