先天性双侧无睾症：12例临床、激素及影像学研究

Congenital bilateral anorchia: clinical, hormonal and imaging study in 12 cases.

作者信息

De Rosa M, Lupoli G, Mennitti M, Zarrilli S, Mirone V, Lombardi G

机构信息

Department of Endocrinology and Molecular and Clinical Oncology, School of Medicine, University Federico II, Naples, Italy.

出版信息

Andrologia. 1996 Sep-Oct;28(5):281-5. doi: 10.1111/j.1439-0272.1996.tb02797.x.

DOI:10.1111/j.1439-0272.1996.tb02797.x

PMID:8893097

Abstract

Twelve anorchid pre-pubertal and post-pubertal patients, aged between 8.5 and 41 years, were studied. The FSH and LH basal levels as well as their responses to Gn-RH (100 micrograms i.v.) were increased and prolonged in the post-pubertal patients. The testosterone levels were in the pre-pubertal range and failed to increase after HCG administration (1500 I.U. t.i.d. for 3 days). Ultrasonography of the pelvis was performed in all the patients. Computed tomography and magnetic resonance of the abdomen were also performed in 6 and 5 patients respectively. These techniques failed to show any testicular tissue. Lastly, in 4 patients, surgical exploration confirmed the absence of testicular structure.

摘要

对12例年龄在8.5至41岁之间的青春期前和青春期后无睾患者进行了研究。青春期后患者的促卵泡生成素（FSH）和促黄体生成素（LH）基础水平及其对促性腺激素释放激素（Gn-RH，静脉注射100微克）的反应增强且延长。睾酮水平处于青春期前范围，在注射人绒毛膜促性腺激素（HCG，1500国际单位，每日3次，共3天）后未能升高。对所有患者均进行了盆腔超声检查。分别对6例和5例患者进行了腹部计算机断层扫描和磁共振成像检查。这些检查技术均未显示任何睾丸组织。最后，在4例患者中，手术探查证实不存在睾丸结构。