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西班牙儿童中循环抗6型人类疱疹病毒IgG抗体的低流行率。

Low prevalence of circulating anti-type 6 human herpes virus IgG-antibodies in Spanish children.

作者信息

Roldan C, Gutiérrez J, de la Higuera A, Maroto C

机构信息

Department of Microbiology, University of Granada, Hospital Universitario San Cecilio, Spain.

出版信息

Microbios. 1996;86(349):233-6.

PMID:8893525
Abstract

The prevalence of circulating anti-HHV-6 IgG-antibodies in an infant population, was investigated to assess the evolution of antibody titres from birth to adulthood. Endpoint titration was done by indirect immunofluorescence, in 525 samples of serum from children, healthy adults and pregnant women. In the children, seropositivity increased from the age of 6 months, and was highest (56.52%) between 7 months and 1 year, suggesting that the initial infection occurred between 6 and 12 months of age.

摘要

为评估从出生到成年抗体滴度的演变情况,对婴儿群体中循环抗人疱疹病毒6型(HHV-6)IgG抗体的流行率进行了调查。通过间接免疫荧光法对525份来自儿童、健康成人及孕妇的血清样本进行终点滴定。在儿童中,血清阳性率从6个月龄开始上升,在7个月至1岁之间最高(56.52%),这表明初次感染发生在6至12个月龄之间。

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