Seki K, Nakasato N, Fujita S, Hatanaka K, Kawamura T, Kanno A, Yoshimoto T
Department of Neurosurgery, Tohoku University School of Medicine, Sendai, Japan.
Electroencephalogr Clin Neurophysiol. 1996 Sep;100(5):436-42.
Visual evoked magnetic fields due to pattern reversal stimuli were measured in 5 normal subjects using a helmet-shaped 66 channel magnetoencephalography system linked to MRI. The magnetic topography of the prominent 100 ms response (P100m) evoked by fullfield visual showed a double-dipole pattern in the occipital areas of all subjects. Right or left half-field stimuli and upper or lower quadrant-field stimuli evoked a single-dipole pattern in the contralateral occipital area. The P100m sources were then localized using a current dipole model and superimposed on MRI images of each subject. The visual cortex was morphologically variable among the subjects, but the P100m dipoles were all localized at the lateral bottom of the calcarine fissure. Moreover, these P100m dipoles had similar orientations for both half-or quadrant-field stimuli. These results suggest that the P100m is located in a smaller part of the striate cortex than previously reported.
使用与磁共振成像（MRI）相连的头盔形66通道脑磁图系统，对5名正常受试者进行了由模式反转刺激引起的视觉诱发电场测量。全视野视觉诱发的突出的100毫秒反应（P100m）的磁地形图在所有受试者的枕叶区域显示出双偶极模式。右半视野或左半视野刺激以及上象限或下象限视野刺激在对侧枕叶区域诱发单偶极模式。然后使用电流偶极模型对P100m源进行定位，并叠加在每个受试者的MRI图像上。受试者之间视觉皮层的形态各不相同，但P100m偶极均位于距状裂的外侧底部。此外，对于半视野或象限视野刺激，这些P100m偶极具有相似的方向。这些结果表明，P100m位于纹状皮层中比先前报道的更小的区域。
