Chong Y Y, Chew C N, Koh E T, Fock K M
Department of Medicine Toa Payoh Hospital, Toa Payoh Rise, Singapore.
Ann Acad Med Singap. 1996 Jul;25(4):496-9.
Two hundred and seventy-seven consecutive cases of peptic ulcer patients were compared. Of these, 103 presented with acute gastrointestinal haemorrhage and 174 presented with pain. The median age of those who bled (53 years) was not significantly higher than those who presented with pain (50 years) (P > 0.05). Bleeding peptic ulcer patients, when compared to non-bleeding ulcer patients, tended to present with a past history of gastrointestinal haemorrhage, have ingested non-steroidal anti-inflammatory drugs, and have, at endoscopy, ulcers greater than 1.5 cm in diameter. The site and number of ulcers did not influence the mode of presentation. About 60% of bleeding ulcers were found in the duodenum and this proportion of duodenal ulcers was not significantly different in both groups of patients. Gastric ulcer patients who bled tended to be significantly associated with ingestion of non-steroidal anti-inflammatory drugs. Gender and ethnic distribution, smoking and alcohol ingestion were all not associated with the presentation of haemorrhage.
对277例连续性消化性溃疡患者进行了比较。其中，103例出现急性胃肠道出血，174例出现疼痛。出血患者的中位年龄（53岁）并不显著高于出现疼痛的患者（50岁）（P>0.05）。与非出血性溃疡患者相比，出血性消化性溃疡患者往往有胃肠道出血病史、服用过非甾体抗炎药，且在内镜检查时溃疡直径大于1.5厘米。溃疡的部位和数量不影响临床表现方式。约60%的出血性溃疡发生在十二指肠，两组患者中十二指肠溃疡的这一比例无显著差异。出血的胃溃疡患者往往与服用非甾体抗炎药有显著关联。性别和种族分布、吸烟和饮酒均与出血的表现无关。
