Lau G
Department of Forensic Medicine Institute of Science and Forensic Medicine, Singapore.
Ann Acad Med Singap. 1996 Jul;25(4):509-15.
An earlier retrospective, clinicopathological review of 132 perioperative Coroner's autopsies (excluding cases of preoperative major trauma), conducted by the Department of Forensic Medicine during the period from January 1989 to December 1991, showed that such cases accounted for an average of 2% of all Coroner's autopsies performed during that time. Of these, 15.2% were iatrogenic deaths which were unrelated to anaesthetic complications. Over the subsequent 3-year period (January 1992 to December 1994), there were 170 similar cases, arising from a total of 6468 Coroner's autopsies, representing a composite necropsy incidence of 2.6% (annual incidence: 2.5% to 2.8%) and an absolute increase of 38 cases over the previous period (P < 0.05). Also, the proportion of non-anaesthetic, iatrogenic deaths almost doubled to 28.8% (P < 0.02). Although these observations do not, considered alone, denote a rise in perioperative mortality during the second period (1992 to 1994), as compared to the first, since both studies were limited to deaths reported to the Coroner, they do seem to emphasize the need for a comprehensive ongoing clinical and medico-legal audit of perioperative deaths locally. At present, the proportion of perioperative deaths which are not reported to the Coroner and, thereby, escape medico-legal review, remains undertermined. In addition, as at the end of June 1995, only 23 of 51 pathologically unnatural deaths received a Coroner's verdict of misadventure, with an additional 11 such cases pending inquiry. This rather wide divergence between medical opinion and legal judgement could be a subject of further research.
法医学系在1989年1月至1991年12月期间,对132例围手术期死因裁判官尸检(不包括术前严重创伤病例)进行了一项早期回顾性临床病理研究,结果显示此类病例平均占该时期所有死因裁判官尸检的2%。其中,15.2%为与麻醉并发症无关的医源性死亡。在随后的3年期间(1992年1月至1994年12月),共有170例类似病例,来自6468例死因裁判官尸检,综合尸检发生率为2.6%(年发生率:2.5%至2.8%),较上一时期绝对增加了38例(P<0.05)。此外,非麻醉性医源性死亡的比例几乎翻了一番,达到28.8%(P<0.02)。尽管仅凭这些观察结果并不能表明第二个时期(1992年至1994年)围手术期死亡率相比第一个时期有所上升,因为两项研究都仅限于向死因裁判官报告的死亡病例,但它们似乎确实强调了在当地对围手术期死亡进行全面持续临床和法医学审计的必要性。目前,未向死因裁判官报告从而未接受法医学审查的围手术期死亡比例仍未确定。此外,截至1995年6月底,51例病理上非自然死亡中只有23例获得死因裁判官意外事故的裁决,另有11例此类案件正在调查中。医学意见和法律判决之间的这种较大差异可能是进一步研究的课题。