Tan K L, Mah P K, Rajasoorya C, Sim C S, Chia F K
Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.
Ann Acad Med Singap. 1996 Jul;25(4):592-5.
Distant metastases due to paraganglioma are a rare occurrence. We report a case of paraganglioma with pulmonary metastases and review the literature on paragangliomas. A 29-year-old female presented with cervical lymphadenopathy, excision biopsy of which confirmed the diagnosis of paraganglioma. She subsequently underwent tumour embolisation and received a course of radiotherapy. Seven years later, she was investigated for multiple pulmonary nodules noted on her chest roentgenogram. Histology of the wedge excision of the lung showed metastatic paraganglioma. Increased catecholamine production was documented; this was however not associated with symptoms of catecholamine excess. Reports concerning the treatment of paragangliomas with pulmonary metastases are few, given their rarity.
副神经节瘤导致的远处转移很少见。我们报告一例伴有肺转移的副神经节瘤病例，并回顾关于副神经节瘤的文献。一名29岁女性因颈部淋巴结肿大就诊，切除活检确诊为副神经节瘤。她随后接受了肿瘤栓塞治疗并接受了一个疗程的放疗。七年后，她因胸部X线片上发现多个肺结节而接受检查。肺楔形切除组织学检查显示为转移性副神经节瘤。记录显示儿茶酚胺分泌增加；然而，这与儿茶酚胺过量症状无关。鉴于其罕见性，关于伴有肺转移的副神经节瘤治疗的报道很少。
