Kumari Kalpana, Jain Deepali, Kumar Rohit, Mohan Anant, Kumar Rakesh
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Department of Pulmonary medicine and sleep disorders, All India Institute of Medical Sciences, New Delhi, India.
Diagn Cytopathol. 2017 Apr;45(4):327-332. doi: 10.1002/dc.23650. Epub 2016 Nov 30.
Paragangliomas are tumors that originate from the extra-adrenal chromaffin and nonchromaffin cells of neural crest origin. Lymph node metastases are common, while distant metastases to lung, liver, and bone are rare events and usually occur in the presence of a long standing clinically evident primary tumor. Primary diagnosis of paraganglioma at a metastatic site without a known primary is a diagnostic challenge. We report a case of an adult woman with incidentally detected metastasis to bilateral lungs from an occult carotid body paraganglioma, which presented a cytopathological diagnostic dilemma on EBUS-TBNA from paratracheal lymph nodes. Diagn. Cytopathol. 2017;45:327-332. © 2016 Wiley Periodicals, Inc.
副神经节瘤是起源于神经嵴来源的肾上腺外嗜铬细胞和非嗜铬细胞的肿瘤。淋巴结转移很常见，而肺、肝和骨的远处转移则很少见，通常发生在长期存在临床明显的原发性肿瘤的情况下。在没有已知原发性肿瘤的转移部位对副神经节瘤进行原发性诊断是一项诊断挑战。我们报告一例成年女性，偶然发现隐匿性颈动脉体副神经节瘤转移至双侧肺，该病例在经支气管超声引导下经气管旁淋巴结针吸活检（EBUS-TBNA）时出现了细胞病理学诊断难题。《诊断细胞病理学》2017年；45:327 - 332。©2016威利期刊公司
