Aylett M, Creighton P, Jachuck S, Newrick D, Evans A
J Hum Hypertens. 1996 Aug;10(8):547-50.
This study examined the blood pressure (BP) control and number of drugs prescribed for a sample of hypertensive patients from 18 practices in Northeast England. Out of a total of 35,379 registered patients aged 40-69 years, 2995 (8.5%) were on treatment for hypertension. Data was abstracted from the practice records of a random sample of 691 patients. Using British Hypertension Society standards, BP control was optimal for systolic pressure (less than 160 mm Hg) in 469 (68%), and for diastolic pressure (less than 90 mm Hg) in 345 (50%), but only 269 (39%) had optimally controlled systolic and diastolic pressures. Sixty-one per cent were taking one drug and 39% two or more; 82% of patients aged 40-49 years but only 61% of those aged 60-69 years had optimally controlled systolic pressures. Forty-three per cent of the 40 to 49-year-old group and 56% of the 60 to 69-year-old group had optimally controlled diastolic pressures. A strong inverse relationship was found between age and systolic BP control but there was no association between age and diastolic pressure or the number of drugs being prescribed. Sub-optimal BP control is a major problem and remedial strategies should stress the greater gain from treating older patients.
本研究调查了英格兰东北部18家医疗机构中部分高血压患者的血压控制情况及所开药物数量。在总共35379名年龄在40 - 69岁的注册患者中，2995名（8.5%）正在接受高血压治疗。数据取自691名患者的随机抽样病历记录。按照英国高血压学会的标准，469名患者（68%）的收缩压控制理想（低于160毫米汞柱），345名患者（50%）的舒张压控制理想（低于90毫米汞柱），但只有269名患者（39%）的收缩压和舒张压都得到了理想控制。61%的患者服用一种药物，39%的患者服用两种或更多药物；40 - 49岁的患者中有82%收缩压得到理想控制，而60 - 69岁的患者中只有61%。40至49岁组中有43%的患者舒张压得到理想控制，60至69岁组中有56%。研究发现年龄与收缩压控制之间存在强烈的负相关关系，但年龄与舒张压或所开药物数量之间没有关联。血压控制不理想是一个主要问题，补救策略应强调治疗老年患者能获得更大益处。
