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α-亚麻酸(18:3ω3)对大鼠γ-亚麻酸(18:3ω6)代谢的影响。

The influence of alpha-linolenic acid (18: 3omega3) on the metabolism of gamma-linolenic acid (18: 3omega6) in the rat.

作者信息

Hassam A G

出版信息

Br J Nutr. 1977 Jul;38(1):137-40. doi: 10.1079/bjn19770069.

DOI:10.1079/bjn19770069
PMID:889767
Abstract
  1. Essential fatty acid-deficient rats were fed gamma-linolenic acid (18: 3omega6) at 2% dietary energy and alpha-linolenic acid (18: 3omega3) at 0, 1-6, 2-8 and 4-0% of the dietary energy. 2. 18: 3omega3 at 1-6% apparently inhibits the synthesis of the C20 and C22 omega6 long-chain polyunsaturated fatty acids (omega6 LC-PUFA) metabolized from 18: 3omega6. 3. However, increasing the dietary levels of 18: 3omega3 from 1-6 to 4-0% has no further influence. 4. The results suggest that dietary 18: 3omega6 is an efficent precursor for the omega6 LC-PUFA synthesis even in the presence of 18: 3omega3.
摘要
  1. 给必需脂肪酸缺乏的大鼠喂食占膳食能量2%的γ-亚麻酸(18:3ω6)以及占膳食能量0%、1 - 6%、2 - 8%和4 - 0%的α-亚麻酸(18:3ω3)。2. 1 - 6%的18:3ω3明显抑制了由18:3ω6代谢而来的C20和C22ω6长链多不饱和脂肪酸(ω6 LC - PUFA)的合成。3. 然而,将18:3ω3的膳食水平从1 - 6%提高到4 - 0%没有进一步影响。4. 结果表明,即使存在18:3ω3,膳食中的18:3ω6仍是ω6 LC - PUFA合成的有效前体。

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1
The influence of alpha-linolenic acid (18: 3omega3) on the metabolism of gamma-linolenic acid (18: 3omega6) in the rat.α-亚麻酸(18:3ω3)对大鼠γ-亚麻酸(18:3ω6)代谢的影响。
Br J Nutr. 1977 Jul;38(1):137-40. doi: 10.1079/bjn19770069.
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Influence of dietary essential fatty acid level on fatty acid composition in peripheral nerve and muscle.
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Potency of gamma-linolenic acid (18:3omega6) in curing essential fatty acid deficiency in the rat.γ-亚麻酸(18:3ω6)对治愈大鼠必需脂肪酸缺乏症的效力。
Nutr Metab. 1977;21 Suppl 1:190-2. doi: 10.1159/000176158.
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[Effect of dietary alpha-linolenic acid on the conversion of linoleic and gamma-linolenic acids (1-14C) into arachidonates in rats in vivo].[膳食α-亚麻酸对大鼠体内亚油酸和γ-亚麻酸(1-¹⁴C)转化为花生四烯酸的影响]
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Linoleic and alpha-linolenic acids differently modify the effects of elaidic acid on polyunsaturated fatty acid metabolism and some immune indices in rats.亚油酸和α-亚麻酸对反油酸在大鼠多不饱和脂肪酸代谢及某些免疫指标方面的影响有着不同的调节作用。
Br J Nutr. 1997 Apr;77(4):645-56. doi: 10.1079/bjn19970062.
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The nutritional and metabolic impact of gamma-linolenic acid (18:3omega6) on cats deprived of animal lipid.γ-亚麻酸(18:3ω6)对缺乏动物脂质的猫的营养和代谢影响。
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Ann Nutr Metab. 1986;30(5):316-23. doi: 10.1159/000177209.

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Acyl group distributions in tissue lipids of rats fed evening primrose oil (λ-linolenic plus linoleic acid) or soybean oil (α-linolenic plus linoleic acid).喂食月见草油(γ-亚麻酸加亚油酸)或大豆油(α-亚麻酸加亚油酸)的大鼠组织脂质中的酰基分布。
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Lipids. 2012 May;47(5):505-17. doi: 10.1007/s11745-012-3660-7. Epub 2012 Feb 26.
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