Koistinen P, Martikkala V, Karpakka J, Vuolteenaho O, Leppäluoto J
Health Centre Hospital of Oulu, Finland.
J Sports Med Phys Fitness. 1996 Jun;36(2):108-11.
To study the effect of moderate altitude on thyroid hormones among training athletes.
Serum total and free triiodothyronine (T3), thyroxine (T4), and thyrotropin (TSH) concentrations were measured among eight training athletes at sea level and subsequently during training for 12 days at the altitude of 1100-2700 m.
Deaconess Institute of Oulu, and Division of Sports Medicine, Department of Physiology, University of Oulu, Finland.
National top class skiers who normally live at sea level.
Serum concentrations of TSH, total and free T4, and reverse T3 did not change significantly. A significant decrease in serum total T3 levels from 1.9 nmol1-1 on days 1-3 to 1.6-1.7 nmoll-1 on days and 5-6 (p < 0.05) was observed. Serum albumin decreased (p < 0.05) on days 1-8 at altitude and correlated to serum total T3 (R = 0.36, p = 0.013). Serum free T3 increased steadily at moderate altitude and reached a significantly higher level (p < 0.05) at the end of the training period than before.
The serum free T3 increases when unacclimatized sea level skiers move to train at moderate altitude.
研究中等海拔对训练运动员甲状腺激素的影响。
在海平面测量了8名训练运动员的血清总三碘甲状腺原氨酸（T3）、游离三碘甲状腺原氨酸、甲状腺素（T4）和促甲状腺激素（TSH）浓度，随后在海拔1100 - 2700米处进行为期12天的训练期间再次测量。
芬兰奥卢女执事研究所及奥卢大学体育医学部生理学系。
通常生活在海平面的国家顶级滑雪运动员。
TSH、总T4、游离T4和反T3的血清浓度无显著变化。观察到血清总T3水平从第1 - 3天的1.9 nmol·L⁻¹显著降至第5 - 6天的1.6 - 1.7 nmol·L⁻¹（p < 0.05）。海拔高度下第1 - 8天血清白蛋白降低（p < 0.05），且与血清总T3相关（R = 0.36，p = 0.013）。中等海拔时血清游离T3稳步升高，训练期结束时达到显著高于之前的水平（p < 0.05）。
未适应的海平面滑雪运动员转移到中等海拔训练时，血清游离T3升高。
