Sologub M I, El-Sayed E M, Grupe R
Biofizika. 1977 May-Jun;22(3):461-4.
Chlorcholine chloride (CCC) the molecule of which has no other group, characteristic of acetylcholine (Ach), causes an effective cholinomimetic action on the surface membrane of the mollusc neurons A and B. As the concentration of Ach and CCC increases from 10(-6) to 10(-3) M the resting potential (RP) and the membrane resistance (R) of the neuron A first increases then decreases. The increase of Ach and CCC concentration causes in the neuron B only a decrease of the above mentioned parameters. The data point to the necessity of improving the ideas about the structure of cholinoreceptors and mechanism of cholinoreceptor-cholinomimetic interaction.
氯化胆碱（CCC）分子不具有乙酰胆碱（Ach）特有的其他基团，却对软体动物神经元A和B的表面膜产生有效的拟胆碱作用。随着Ach和CCC的浓度从10⁻⁶增加到10⁻³ M，神经元A的静息电位（RP）和膜电阻（R）先增加后降低。Ach和CCC浓度的增加仅导致神经元B上述参数的降低。这些数据表明有必要完善关于胆碱能受体结构和胆碱能受体-拟胆碱药物相互作用机制的观点。
