重氮甲烷在15-氧代-前列腺素F2α定量分析中的局限性。
Limitations of diazomethane for the quantification of 15-oxo-prostaglandin F2alpha.
作者信息
Cockerill A F, Gutteridge N J, Mallen D N, Osborne D J, Rackham D M
出版信息
Biomed Mass Spectrom. 1977 Jun;4(3):187-9. doi: 10.1002/bms.1200040312.
PMID:890080
Abstract
The relatively rapid formation of pyrazoline adducts is a serious side reaction in the esterification of 15-oxo-PGF2alpha with ethereal diazomethane under conditions used routinely in the chemical derivatization of prostaglandins.
摘要
在前列腺素化学衍生化常规使用的条件下，用乙醚重氮甲烷对15-氧代-PGF2α进行酯化时，吡唑啉加合物相对快速的形成是一种严重的副反应。
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