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一些新型4H-吡喃并[3,2-c]苯并吡喃-5-酮衍生物的合成、反应及其潜在生物活性

Synthesis and reactions of some new 4H-pyrano[3,2-c]benzopyran-5-one derivatives and their potential biological activities.

作者信息

Shaker R M

机构信息

Chemistry Department, El-Minia University, Egypt.

出版信息

Pharmazie. 1996 Mar;51(3):148-51.

PMID:8900865
Abstract

Several new 4H-pyrano[3,2-c]benzopyran-5-ones (6a-g and 10) which exhibited antibacterial and fungicidal activity, have been synthesized via a one flask multicomponent condensation of aldehydes with malononitrile and 4-hydroxycoumarin. The reactions of 6a with several nucleophilic reagents are reported.

摘要

通过醛与丙二腈和4-羟基香豆素的单瓶多组分缩合反应，合成了几种具有抗菌和杀菌活性的新型4H-吡喃并[3,2-c]苯并吡喃-5-酮（6a-g和10）。报道了6a与几种亲核试剂的反应。

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