Harland G B, Okafo G, Matejtschuk P, Sellick I C, Chapman G E, Camilleri P
SmithKline Beecham Pharmaceuticals, Welwyn, Herts, UK.
Electrophoresis. 1996 Feb;17(2):406-11. doi: 10.1002/elps.1150170220.
Capillary electrophoresis and laser-induced fluorescence detection have been used to fingerprint the 2-aminoacridone derivatives of complex glycans released from bovine fetuin and human IgG monoclonal antibodies. The utility of this method in distinguishing between N- and O-linked oligosaccharides and in determining the presence of sialic acid residues in glycan mixtures at an early stage of analysis has been demonstrated.
毛细管电泳和激光诱导荧光检测已被用于对从牛胎球蛋白和人IgG单克隆抗体释放的复合聚糖的2-氨基吖啶酮衍生物进行指纹识别。该方法在分析早期区分N-连接和O-连接寡糖以及确定聚糖混合物中唾液酸残基存在情况的实用性已得到证明。
