Fox K A, Rudge F W
USAFSAM/AF, Brooks AFB, TX 78235-5123, USA.
Aviat Space Environ Med. 1996 Apr;67(4):376-8.
Autosomal dominant polycystic kidney disease is a relatively common familial disorder which frequently affects multiple organ systems. The condition is associated with hypertension, cardiac valvular abnormalities, cerebral berry aneurysms, and chronic renal failure. We describe an aviator with a long history of hypertension that was found to be due to autosomal dominant polycystic kidney disease. Following an extensive evaluation, he was found capable of continuation of flying duties. The epidemiology, pathogenesis, diagnosis, evaluation, and aeromedical implications of autosomal dominant polycystic kidney disease in an aviator are discussed.
常染色体显性多囊肾病是一种相对常见的家族性疾病，常累及多个器官系统。该疾病与高血压、心脏瓣膜异常、脑动脉瘤和慢性肾衰竭有关。我们描述了一名有长期高血压病史的飞行员，发现其高血压是由常染色体显性多囊肾病引起的。经过全面评估，发现他能够继续履行飞行职责。本文讨论了常染色体显性多囊肾病在飞行员中的流行病学、发病机制、诊断、评估及航空医学意义。
