Inestrosa N C, Sunkel C E, Arriagada J, Garrido J, Godoy-Herrera R
Departamento de Biología Celular y Molecular, Pontificia Universidad Católica de Chile.
Genetica. 1996 Mar;97(2):205-10. doi: 10.1007/BF00054627.
The yellow (y) mutation of Drosophila melanogaster affects the development of behavior and morphology. We have analyzed some behavioral and morphological parameters during the development of y mutants. Wild-type third instar larvae move in straighter paths than larvae of the same age homozygous for the y mutation. At 96 h of age, the tracks of y larvae have 10 times as many loops as tracks of wild-type larvae, and at 120 h of age, y larvae show bending behavior about 2.5 times more frequently than do wild-type. Consequently, they do not disperse as much as wild-type larvae. Concomitant with the behavioral changes, the larvae present a defect in the morphology of large chaetae in the larval denticle belts, particularly of 2nd and 3rd instars, both with light and scanning electron microscopes. These results suggest that a cuticular defect is probably involved in the abnormal locomotor activity observed in y larvae of Drosophila melanogaster.
黑腹果蝇的黄色（y）突变会影响行为和形态的发育。我们分析了y突变体发育过程中的一些行为和形态参数。野生型三龄幼虫比y突变纯合的同龄幼虫移动路径更直。在96小时龄时，y幼虫的轨迹比野生型幼虫的轨迹多10倍的环，在120小时龄时，y幼虫表现出弯曲行为的频率比野生型高约2.5倍。因此，它们不像野生型幼虫那样分散。与行为变化同时发生的是，用光学显微镜和扫描电子显微镜观察发现，幼虫在幼虫齿带中的大刚毛形态存在缺陷，尤其是二龄和三龄幼虫。这些结果表明，表皮缺陷可能与黑腹果蝇y幼虫中观察到的异常运动活动有关。
