Dufresne A, Loosereewanich P, Armstrong B, Thériault G, Bégin R
Department of Occupational Health, McGill University, Montréal, Québec, Canada.
Am Ind Hyg Assoc J. 1996 Apr;57(4):370-5. doi: 10.1080/15428119691014918.
This paper reports on the inorganic particles in the lungs of four workers who died from lung cancer and one who died from mesothelioma. All five workers were involved in different operations and activities in aluminum reduction plants. Retained fibrous and nonfibrous particles were evaluated by transmission electron microscopy and energy dispersive spectroscopy after lung digestion. Asbestos fibers, fragments of silicates, and metal-rich nonfibrous particles of chromium-cobalt and aluminum were detected. Conclusions drawn from the evaluation of the particles retained in the lungs of only five workers must be cautious. However, these results are consistent with the hypothesis that carcinogenic polycyclic aromatic hydrocarbons may not be the only contaminants that could explain excess mortality from malignant lung neoplasm in aluminum smelter workers.
本文报告了4名死于肺癌和1名死于间皮瘤的工人肺部的无机颗粒情况。这5名工人均参与了铝冶炼厂的不同作业和活动。在对肺部进行消化处理后，通过透射电子显微镜和能量色散光谱对留存的纤维状和非纤维状颗粒进行了评估。检测到了石棉纤维、硅酸盐碎片以及富含铬 - 钴和铝的金属非纤维颗粒。仅基于5名工人肺部留存颗粒的评估得出的结论必须谨慎。然而，这些结果与以下假设一致，即致癌多环芳烃可能并非是能够解释铝冶炼厂工人恶性肺肿瘤超额死亡率的唯一污染物。
