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Evidence for dopamine deamination by both type A and type B monoamine oxidase in rat brain in vivo and for the degree of inhibition of enzyme necessary for increased functional activity of dopamine and 5-hydroxytryptamine.

作者信息

Green A R, Mitchell B D, Tordoff A F, Youdim M B

出版信息

Br J Pharmacol. 1977 Jul;60(3):343-9. doi: 10.1111/j.1476-5381.1977.tb07506.x.

DOI:10.1111/j.1476-5381.1977.tb07506.x
PMID:890205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1667291/
Abstract
摘要

相似文献

1
Evidence for dopamine deamination by both type A and type B monoamine oxidase in rat brain in vivo and for the degree of inhibition of enzyme necessary for increased functional activity of dopamine and 5-hydroxytryptamine.大鼠脑内A型和B型单胺氧化酶对多巴胺脱氨基作用的体内证据，以及多巴胺和5-羟色胺功能活性增强所需的酶抑制程度。
Br J Pharmacol. 1977 Jul;60(3):343-9. doi: 10.1111/j.1476-5381.1977.tb07506.x.
2
Effects of monoamine oxidase inhibition by clorgyline, deprenil or tranylcypromine on 5-hydroxytryptamine concentrations in rat brain and hyperactivity following subsequent tryptophan administration.氯吉兰、丙炔苯丙胺或反苯环丙胺抑制单胺氧化酶对大鼠脑内5-羟色胺浓度及随后给予色氨酸后的多动的影响。
Br J Pharmacol. 1975 Nov;55(3):415-22. doi: 10.1111/j.1476-5381.1975.tb06946.x.
3
Preferential deamination of dopamine by an A type monoamine oxidase in rat brain.大鼠脑中A型单胺氧化酶对多巴胺的优先脱氨基作用。
Naunyn Schmiedebergs Arch Pharmacol. 1976;292(1):9-14. doi: 10.1007/BF00506483.
4
Studies in vivo on the relationship between brain tryptophan, brain 5-HT synthesis and hyperactivity in rats treated with a monoamine oxidase inhibitor and L-tryptophan.关于用单胺氧化酶抑制剂和L-色氨酸处理的大鼠中脑色氨酸、脑5-羟色胺合成与多动之间关系的体内研究。
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5
Species differences in the deamination of dopamine and other substrates for monoamine oxidase in brain.大脑中多巴胺及单胺氧化酶其他底物脱氨基作用的物种差异。
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6
A and B forms of monoamine oxidase within the monoaminergic neurons of the rat brain.大鼠脑单胺能神经元内单胺氧化酶的A和B形式。
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7
Deamination of norepinephrine, dopamine, and serotonin by type A monoamine oxidase in discrete regions of the rat brain and inhibition by RS-8359.大鼠脑离散区域中A型单胺氧化酶对去甲肾上腺素、多巴胺和5-羟色胺的脱氨基作用以及RS-8359的抑制作用
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The deamination of dopamine by human brain monoamine oxidase. Specificity for the two enzyme forms in seven brain regions.人脑海马单胺氧化酶对多巴胺的脱氨基作用。七个脑区中两种酶形式的特异性。
Naunyn Schmiedebergs Arch Pharmacol. 1983 Apr;322(3):198-202. doi: 10.1007/BF00500765.
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Responses of developing rats to L-tryptophan plus an MAOI-I. Monitoring changes in behaviour, brain 5-HT and tryptophan.
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Chronic monoamine oxidase-B inhibitor treatment blocks monoamine oxidase-A enzyme activity.慢性单胺氧化酶-B 抑制剂治疗可阻断单胺氧化酶-A 酶活性。
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本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
A SENSITIVE METHOD FOR SPECTROPHOTOFLUOROMETRIC ASSAY OF CATECHOLAMINES.一种用于儿茶酚胺分光光度荧光测定的灵敏方法。
Int J Neuropharmacol. 1964 Dec;3:643-9. doi: 10.1016/0028-3908(64)90089-9.
3
Rapid method for the determination of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in small regions of rat brain.大鼠脑小区域中5-羟色胺和5-羟吲哚乙酸的快速测定方法。
Br J Pharmacol. 1970 Jul;39(3):653-5. doi: 10.1111/j.1476-5381.1970.tb10373.x.
4
L-DOPA: effect on concentrations of dopamine, norepinephrine, and serotonin in brains of mice.左旋多巴：对小鼠大脑中多巴胺、去甲肾上腺素和血清素浓度的影响。
Science. 1970 May 15;168(3933):847-50.
5
The monoamine oxidases of brain: selective inhibition with drugs and the consequences for the metabolism of the biogenic amines.大脑中的单胺氧化酶：药物的选择性抑制及其对生物胺代谢的影响。
J Pharmacol Exp Ther. 1974 Jun;189(3):733-40.
6
Human brain monoamine oxidase: multiple forms and selective inhibitors.人类大脑单胺氧化酶：多种形式与选择性抑制剂
Nature. 1972 Mar 31;236(5344):225-8. doi: 10.1038/236225b0.
7
The role of brain dopamine in the hyperactivity syndrome produced by increased 5-hydroxytryptamine synthesis in rats.脑多巴胺在大鼠5-羟色胺合成增加所产生的多动综合征中的作用。
Neuropharmacology. 1974 Nov;13(10-11):949-59. doi: 10.1016/0028-3908(74)90086-0.
8
Studies in vivo on the relationship between brain tryptophan, brain 5-HT synthesis and hyperactivity in rats treated with a monoamine oxidase inhibitor and L-tryptophan.关于用单胺氧化酶抑制剂和L-色氨酸处理的大鼠中脑色氨酸、脑5-羟色胺合成与多动之间关系的体内研究。
J Neurochem. 1971 Jun;18(6):1053-66. doi: 10.1111/j.1471-4159.1971.tb12034.x.
9
Evidence concerning the involvement of 5-hydroxytryptamine in the locomotor activity produced by amphetamine or tranylcypromine plus L-DOPA.关于5-羟色胺参与苯丙胺或反苯环丙胺加左旋多巴所产生的运动活动的证据。
Br J Pharmacol. 1976 May;57(1):141-7. doi: 10.1111/j.1476-5381.1976.tb07664.x.
10
Effects of monoamine oxidase inhibition by clorgyline, deprenil or tranylcypromine on 5-hydroxytryptamine concentrations in rat brain and hyperactivity following subsequent tryptophan administration.氯吉兰、丙炔苯丙胺或反苯环丙胺抑制单胺氧化酶对大鼠脑内5-羟色胺浓度及随后给予色氨酸后的多动的影响。
Br J Pharmacol. 1975 Nov;55(3):415-22. doi: 10.1111/j.1476-5381.1975.tb06946.x.