Sellman J D, Joyce P R
Department of Psychological Medicine, Christchurch School of Medicine, New Zealand.
Aust N Z J Psychiatry. 1996 Oct;30(5):573-8. doi: 10.3109/00048679609062652.
To investigate whether depression measured at the time of treatment predicts relapse of alcohol dependence in the 6 months following treatment of alcohol-dependent men.
Ninety-three subjects with moderate-severe alcohol dependence (DSM-III-R), recruited from a 3-week, abstinence-focused therapeutic program, were assessed for current and lifetime major depression using the SCID-P and baseline depressive symptoms using the SCL-90, and then followed up for 6 months. Drinking outcomes were based on multiple sources of data.
Relapse was not associated with either lifetime major depression, or baseline depressive symptoms; inadequate numbers of subjects with a current major depression precluded statistical analysis of this variable.
Neither lifetime major depression, nor the degree of depressive symptoms in alcohol-dependent men at the time of treatment, compromise drinking outcomes in the 6 months following treatment.
调查在治疗酒精依赖男性时所测量的抑郁症状是否能预测治疗后6个月内酒精依赖的复发情况。
从一个为期3周、以戒酒为重点的治疗项目中招募了93名中度至重度酒精依赖(DSM-III-R)患者,使用SCID-P评估当前和终生的重度抑郁情况,使用SCL-90评估基线抑郁症状,然后进行6个月的随访。饮酒结果基于多种数据来源。
复发与终生重度抑郁或基线抑郁症状均无关联;当前患有重度抑郁的受试者数量不足,无法对该变量进行统计分析。
无论是终生重度抑郁,还是酒精依赖男性在治疗时的抑郁症状程度,均不会影响治疗后6个月内的饮酒结果。