Grenier J F, Dauchel J, Marescaux J, Eloy M R, Schang J C
Br J Surg. 1977 Feb;64(2):96-9. doi: 10.1002/bjs.1800640205.
Two cases of end-to-end and end-to-side jejuno-ileal bypass for the treatment of obesity are reported in which both patients underwent reoperation 17 and 23 months later respectively. Macroscopic examination and measurements of length of the various segments of the small intestine have been performed twice in each patient: at the time of the bypass and at the second surgical procedure. In one patient a histological study of both the excluded and functioning small intestine was carried out at the time of each surgical procedure. The functioning intestine had increased in size while the excluded segment had become narrowed. The height of the villi had increased slightly in the functioning ileum and more so in the functioning jejunum compared with the preoperative measurements. In contrast, the height of the villi was moderately reduced in both the bypassed jejunal and ileal segments. These findings confirm the results of experimental studies in animals.
报告了两例采用空肠-回肠端端和端侧吻合术治疗肥胖症的病例,两名患者分别在17个月和23个月后接受了再次手术。对每位患者的小肠各段进行了两次宏观检查和长度测量:一次在旁路手术时,另一次在第二次手术时。其中一名患者在每次手术时都对旷置和发挥功能的小肠进行了组织学研究。发挥功能的肠段尺寸增大,而旷置段变窄。与术前测量结果相比,发挥功能的回肠绒毛高度略有增加,发挥功能的空肠绒毛高度增加更明显。相比之下,旁路的空肠和回肠段绒毛高度均有适度降低。这些发现证实了动物实验研究的结果。