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A novel beta-galactoside-binding lectin in cultured murine lymphocytic leukemia cells.

作者信息

Mai A, Jung S K, Tachikawa H, Fujimoto D

机构信息

Department of Applied Biological Science, Faculty of Agriculture, Tokyo University of Agriculture and Technology.

出版信息

J Biochem. 1996 Sep;120(3):478-80. doi: 10.1093/oxfordjournals.jbchem.a021436.

Abstract

Using affinity chromatography on lactosyl-Sepharose, a beta-galactoside-binding protein of 38 kDa was detected in mouse L1210 lymphocytic leukemia cells. Immunoblotting analysis revealed that it is distinct from any known larger molecular weight galectin. The partial amino acid sequences of the 38 kDa protein indicated that it is a novel member of the galectin family. This 38 kDa lectin is expressed in lymphocytic cell lines but not macrophage-like cell lines.

摘要

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