Proctor D F
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Otolaryngol Head Neck Surg. 1996 Nov;115(5):388-90. doi: 10.1177/019459989611500503.
Nasopharyngeal radium irradiation was a medical treatment that replaced eustachian tube inflation and was itself replaced by tympanotomy tubes. Research and development began in 1924 when Samuel J. Crowe was awarded funds to develop an otologic research laboratory. He observed that recurring adenoids and serous otitis were associated with childhood deafness. In collaboration with Curtis Burnam, he developed a nasopharyngeal radon applicator in the 1930s. This was modified in the 1940s to a nasopharyngeal radium applicator, which had a much longer half-life and did not need treatment lengths recalculated twice each day. Numerous reports on the clinical use of nasopharyngeal radium irradiation in the United States were published. Papers have cautioned against possible dangers of nasopharyngeal radium irradiation, but there have been no substantiated reports. This report ends with three concluding suggestions for research.
鼻咽镭照射是一种取代咽鼓管吹张术的医学治疗方法，而其本身又被鼓膜切开置管术所取代。研发工作始于1924年，当时塞缪尔·J·克罗获得资金以建立一个耳科研究实验室。他观察到复发性腺样体炎和浆液性中耳炎与儿童期耳聋有关。在与柯蒂斯·伯纳姆的合作中，他在20世纪30年代研制出一种鼻咽氡施源器。该施源器在20世纪40年代被改进为鼻咽镭施源器，其半衰期长得多，且无需每天重新计算两次治疗时长。美国发表了许多关于鼻咽镭照射临床应用的报告。有论文告诫了鼻咽镭照射可能存在的危险，但尚无经证实的报告。本报告最后提出了三条研究结论性建议。
