Diwu Z J, Haugland R P, Liu J, Lown J W, Miller G G, Moore R B, Brown K, Tulip J, McPhee M S
Organic Research, Molecular Probes, Inc., Eugene, OR, USA.
Free Radic Biol Med. 1996;20(4):589-93. doi: 10.1016/0891-5849(95)02061-6.
Hypocrellins are under intensive investigation as photosensitizing agents for photodynamic therapy (PDT). A recent advance in the synthesis of hypocrellin congeners resulted in the production of an amino-substituted hypocrellin-B, and its "half chromophore." Both compounds exhibit stronger red light absorption than previously reported hypocrellins, and, therefore, merit investigation as photosensitizers.
