进食后肝脏血流变化的评估——吲哚菁绿清除率与超声多普勒的比较
Assessment of changes in liver blood flow after food intake--comparison of ICG clearance and echo-Doppler.
作者信息
Burggraaf J, Schoemaker H C, Cohen A F
机构信息
Centre for Human Drug Research, Leiden, The Netherlands.
出版信息
Br J Clin Pharmacol. 1996 Oct;42(4):499-502. doi: 10.1046/j.1365-2125.1996.44115.x.
Abstract
Echo-Doppler measurements of portal venous blood flow in intrahepatic branches and indocyanine green (ICG) clearance after continuous i.v. infusion as measure for liver blood flow were compared to evaluate the increase in splanchnic blood flow after food intake. It was shown that both methods assessed the changes in flow in a similar manner. Changes in blood flow in intrahepatic portal vein branches measured with echo-Doppler adequately predicted the change in ICG concentrations. Hence, echo-Doppler measurements of hepatic portal blood flow in intrahepatic branches can be used to estimate changes in total liver blood flow.
摘要
通过超声多普勒测量肝内分支门静脉血流，并比较持续静脉输注后吲哚菁绿（ICG）清除率作为肝血流的测量指标，以评估进食后内脏血流的增加情况。结果表明，两种方法评估血流变化的方式相似。用超声多普勒测量的肝内门静脉分支血流变化能充分预测ICG浓度的变化。因此，超声多普勒测量肝内分支门静脉血流可用于估计肝脏总血流的变化。
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