Whittaker C J, Klier C M, Kolenbrander P E
Laboratory of Microbial Ecology, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20892, USA.
Annu Rev Microbiol. 1996;50:513-52. doi: 10.1146/annurev.micro.50.1.513.
Adherence to a surface is a key element for colonization of the human oral cavity by the more than 500 bacterial taxa recorded from oral samples. Three surfaces are available: teeth, epithelial mucosa, and the nascent surface created as each new bacterial cell binds to existing dental plaque. Oral bacteria exhibit specificity for their respective colonization sites. Such specificity is directed by adhesin-receptor cognate pairs on genetically distinct cells. Colonization is successful when adherent cells grow and metabolically participate in the oral bacterial community. The potential roles of adherence-relevant molecules are discussed in the context of the dynamic nature of the oral econiche.
对于从口腔样本中记录的500多种细菌分类群而言，附着于表面是其在人类口腔中定殖的关键因素。有三种表面可供细菌附着：牙齿、上皮黏膜，以及随着每个新细菌细胞与现有牙菌斑结合而产生的新生表面。口腔细菌对各自的定殖位点具有特异性。这种特异性由遗传上不同的细胞上的粘附素-受体同源对所引导。当附着的细胞生长并在代谢上参与口腔细菌群落时，定殖就成功了。在口腔生态位的动态性质背景下讨论了与粘附相关分子的潜在作用。
