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主动脉瓣急性心内膜炎合并瓣周脓肿的外科治疗:使用机械置换装置的合理考量

Surgical treatment of acute endocarditis of the aortic valve with paravalvular abscess: considerations justifying the use of mechanical replacement devices.

作者信息

Bauernschmitt R, Vahl C F, Lange R, Jakob H, Hagl S

机构信息

Department of Cardiac Surgery, University of Heidelberg, Germany.

出版信息

Eur J Cardiothorac Surg. 1996;10(9):741-7. doi: 10.1016/s1010-7940(96)80334-4.

DOI:10.1016/s1010-7940(96)80334-4
PMID:8905276
Abstract

OBJECTIVE

Early recurrency after surgery for acute endocarditis is a life-threatening complication. Allograft valves are supposed to have a higher resistance to recurrent infection, thus several authors claim them to be the replacement device of choice in cases of aortic endocarditis. However, allografts have two major drawbacks: their availability is limited, and most of the patients require reoperation for graft calcification of degeneration. Until now there has been no prospective study analysing whether early recurrency after surgery of acute endocarditis is associated with the mechanical valve per se or with factors related to the surgical technique or postoperative care.

PATIENTS AND METHODS

We present a prospective study on 36 consecutive patients with acute endocarditis of the aortic valve with paravalvular abscesses. In this series, there were 5 women and 31 men with a mean age of 50.3 years. All patients were operated before a course of antibiotic therapy was completed. Abscesses were radically resected and the cavities closed either with direct suture or, if not possible, with Dacron patches. For aortic valve replacement, a mechanical valve was used in every patient.

RESULTS

The early mortality in this series was 14%, only one patient experienced recurrent endocarditis and underwent reoperation. The results compare well with those achieved after valve replacements with allograft valves.

CONCLUSION

We conclude that, even in cases of acute endocarditis, replacement of the aortic valve with a mechanical device is an acceptable alternative to the allograft, if radical surgical debridement and adequate antibiotic therapy are performed.

摘要

目的

急性心内膜炎手术后的早期复发是一种危及生命的并发症。同种异体移植瓣膜被认为对复发性感染具有更高的抵抗力,因此一些作者声称它们是主动脉心内膜炎病例中首选的置换装置。然而,同种异体移植瓣膜有两个主要缺点:其可用性有限,并且大多数患者需要因移植瓣膜钙化或退化而再次手术。到目前为止,尚无前瞻性研究分析急性心内膜炎手术后的早期复发是与机械瓣膜本身相关,还是与手术技术或术后护理相关的因素有关。

患者与方法

我们对36例连续的伴有瓣周脓肿的主动脉瓣急性心内膜炎患者进行了一项前瞻性研究。在这个系列中,有5名女性和31名男性,平均年龄为50.3岁。所有患者在完成抗生素治疗疗程之前均接受了手术。脓肿被彻底切除,腔隙用直接缝合或(如果不可能)用涤纶补片封闭。对于主动脉瓣置换,每位患者均使用了机械瓣膜。

结果

该系列中的早期死亡率为14%,只有一名患者发生复发性心内膜炎并接受了再次手术。结果与同种异体移植瓣膜置换后的结果相当。

结论

我们得出结论,即使在急性心内膜炎病例中,如果进行了彻底的手术清创和充分的抗生素治疗,用机械装置置换主动脉瓣是同种异体移植的一种可接受的替代方法。

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[Infective endocarditis: considerations regarding optimal timing for surgical treatment].
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