Roisin A J, Prazuck T, Tall F, Sanou J, Cot M, Ballereau F V
USAID Ouagadougou, Burkina Faso.
Eur J Epidemiol. 1996 Oct;12(5):535-7. doi: 10.1007/BF00144008.
A case-control study was carried out to identify risk factors for neonatal tetanus in rural Burkina Faso. Each of the 31 cases identified prospectively were matched with two controls. Risk factors such as the instrument used to cut the umbilical cord and the qualification of the midwives were only identified in the univariate analysis. The multifactorial analysis identified factors commonly believed to be associated with neonatal tetanus: lack of mother's immunization and place of birth other than maternity clinics. However, applying karite nut butter on the umbilical cord was found to be a strong independent factor associated with neonatal tetanus. Immunization of mothers against tetanus should be enforced. Health education must take into consideration sociocultural realities of these populations.
在布基纳法索农村地区开展了一项病例对照研究，以确定新生儿破伤风的风险因素。前瞻性确定的31例病例，每例都与两名对照进行匹配。在单因素分析中仅确定了诸如用于切断脐带的器械以及助产士资质等风险因素。多因素分析确定了通常认为与新生儿破伤风相关的因素：母亲未接种疫苗以及出生地不是产科诊所。然而，发现将乳木果油涂抹在脐带上是与新生儿破伤风相关的一个强有力的独立因素。应加强母亲的破伤风免疫接种。健康教育必须考虑这些人群的社会文化现实。
