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产前破伤风免疫及与新生儿破伤风相关的其他做法。

Prenatal tetanus immunization and other practices associated with neonatal tetanus.

作者信息

Baltazar J C, Sarol J N

机构信息

San Lazaro Hospital, Manila, Philippines.

出版信息

Southeast Asian J Trop Med Public Health. 1994 Mar;25(1):132-8.

PMID:7825003
Abstract

The relationship between neonatal tetanus (NT) on one hand, and maternal tetanus immunization and other prenatal and natal practices on the other hand, was examined in a case-control study done at San Lazaro Hospital (SLH) in Manila from late 1990 to mid 1991. Included as cases were 54 patients diagnosed as NT on the basis of WHO criteria, and 50 controls who were patients 0-4 months of age, hospitalized at SLH during the study period and with no past history of tetanus. The result showed that the following were statistically associated with the risk of NT: home delivery (OR = 30.5); delivered by a traditional birth attendant (OR = 5.2); use of instrument other than scissors to cut the cord (OR = 19.3); traditional birth attendant who dressed the cord (OR = 12.7); and having less than two doses of tetanus toxoid (OR = 15.3). The need to intensify prenatal tetanus immunization, health education of the mothers as well as the training of birth attendants is evident from this study if NT has to be prevented.

摘要

1990年末至1991年年中,在马尼拉的圣拉萨罗医院(SLH)开展了一项病例对照研究,探究了新生儿破伤风(NT)与产妇破伤风免疫以及其他产前和分娩期做法之间的关系。病例组纳入了54例根据世界卫生组织标准诊断为NT的患者,对照组为50名0至4个月大的患者,他们在研究期间住院于SLH,且无破伤风既往史。结果显示,以下因素与NT风险在统计学上相关:在家分娩(比值比[OR]=30.5);由传统助产士接生(OR=5.2);使用剪刀以外的器械剪脐带(OR=19.3);传统助产士处理脐带(OR=12.7);以及破伤风类毒素接种少于两剂(OR=15.3)。如果要预防NT,从本研究可以明显看出加强产前破伤风免疫、对母亲进行健康教育以及培训助产士的必要性。

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