Wakusawa R, Shibata S, Okada K
Can Anaesth Soc J. 1977 Jul;24(4):491-504. doi: 10.1007/BF03005454.
Results of open cardiac surgery under deep simple hypothermia in 121 infants with body weight of less than 10 kg are reported. Deep ether anaesthesia combined with large quantities of ganglion blocking agents (triflupromazine 3 mg/kg) constitutes the anaesthetic management of choice for deep surface-induced hypothermia. The mean lowest oesophageal temperature was 20.8 degrees C, and 18.9 degrees C rectally. The mean circulatory arrest time was 40 minutes. Seventeen infants (14.0 per cent) died post-operatively. There were no operative deaths attributable to failure of cardiac resuscitation. This technique widens the scope of open heart surgery in small infants. Most of the surgically correctable malformations should be operable by this method. More than the potential hazards of hypothermia, which we believe are solved by our technique, the major problem posed by surgery in these small infants is the trans and post-operative respiratory management.
报告了121例体重不足10公斤婴儿在深度单纯低温下进行心脏直视手术的结果。深度乙醚麻醉联合大量神经节阻滞剂（三氟拉嗪3毫克/公斤）是深度体表降温麻醉管理的首选方法。平均最低食管温度为20.8摄氏度，直肠温度为18.9摄氏度。平均循环阻断时间为40分钟。17例婴儿（14.0%）术后死亡。没有因心脏复苏失败导致的手术死亡。该技术拓宽了小婴儿心脏直视手术的范围。大多数可手术纠正的畸形通过这种方法应该可以进行手术。除了我们认为通过我们的技术可以解决的低温潜在危害外，这些小婴儿手术带来的主要问题是术中及术后的呼吸管理。
