Pooley R W, Hayes C J, Edie R N, Gersony W M, Bowman F O, Malm J R
Ann Thorac Surg. 1976 Nov;22(5):415-23. doi: 10.1016/s0003-4975(10)64449-9.
During the 9-year period from 1967 through 1975, 124 open-heart operations were performed on infants less than 1 year of age with 35 operative deaths (28%). Ninety-seven of these procedures used continuous cardiopulmonary bypass with normothermia or mild hypothermia, and 27 were done under deep hypothermia and circulatory arrest. Mortality and morbidity were similar regardless of the operative technique, although deep hypothermia facilitated the repair of complex lesions. The highest mortality occurred in infants less than 3 months of age. Respiratory insufficiency, usually requiring prolonged ventilatory support, occurred only among infants who had pulmonary overcirculation or congestion prior to operation. Adequacy of intraoperative repair and postoperative care were the major determinants of survival.
在1967年至1975年的9年期间，对1岁以下婴儿进行了124例心脏直视手术，其中35例手术死亡（28%）。这些手术中有97例采用常温或轻度低温下的持续心肺转流，27例在深度低温和循环停止下进行。尽管深度低温有助于复杂病变的修复，但无论采用何种手术技术，死亡率和发病率相似。最高死亡率发生在3个月以下的婴儿中。呼吸功能不全通常需要长时间的通气支持，仅发生在术前有肺过度循环或充血的婴儿中。术中修复和术后护理的充分性是生存的主要决定因素。
