Phosphonolipids. XXVII. Synthesis of phosphonic acid analogs of saturated and unsaturated L-alpha-lecithins.
作者信息
Robinson R, Baer E
出版信息
Can J Biochem. 1977 Aug;55(8):907-10. doi: 10.1139/o77-134.
DOI:10.1139/o77-134
PMID:890584
Abstract
A procedure for the synthesis of saturated and unsaturated phosphonolecithin from the cadmium chloride complex of sn-glycerol-3-(2-trimethylammoniumethyl)-phosphonate is reported. The phosphonolecithins are obtained by acylating sn-glycerol-3(2-trimethylammoniumethyl)-phosphonate-cadmium chloride complex with fatty acid chloride and pyridine at low temperature. The preparation of the disteraroyl, dipalmitoyl, dimyristoly, and dioleoyl phosphonolecithins by this procedure is described.
摘要
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