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七氟烷吸入可减轻拔管后支气管痉挛

[Sevoflurane inhalation reduced bronchospasm after extubation].

作者信息

Hamanaka N, Taniguchi A, Tanigami H, Yoshiya I

机构信息

Department of Anesthesiology, Osaka University Medical School, Suita.

出版信息

Masui. 1996 Sep;45(9):1131-4.

PMID:8905951
Abstract

A 73-year-old female was scheduled for left upper lobectomy. She had no history of asthma or chronic obstructive pulmonary disease. During the operation, respiratory sound was clear. As spontaneous breathing was regular and stable after the reversal of neuromuscular blockade, an endotracheal tube was extubated. But soon after the extubation, wheezing and gasping respiration occurred and she complained of dyspnea. Therefore, we administered aminophylline and steroid intravenously, and the patient's lungs were ventilated manually with 100% oxygen. But after 10 minutes, there was no improvement in symptoms, and sevoflurane inhalation was started immediately. Inspiratory sevoflurane concentration was 4% at first, and was decreased to 2%. About 20 minutes after starting sevoflurane inhalation, wheezing was reduced. Sevoflurane may be useful in the treatment of bronchospasm after extubation.

摘要

一名73岁女性计划接受左肺上叶切除术。她没有哮喘或慢性阻塞性肺疾病史。手术过程中,呼吸音清晰。由于在神经肌肉阻滞逆转后自主呼吸规律且稳定,于是拔除了气管内插管。但拔管后不久,患者出现喘息和急促呼吸,并主诉呼吸困难。因此,我们静脉注射了氨茶碱和类固醇,并使用100%氧气对患者肺部进行手动通气。但10分钟后,症状没有改善,立即开始吸入七氟醚。最初吸入七氟醚的浓度为4%,之后降至2%。吸入七氟醚约20分钟后,喘息减轻。七氟醚可能对拔管后支气管痉挛的治疗有用。

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