Kato Y, Kokubo Y, Narita Y, Kuzuhara S, Naito Y
Department of Neurology, Mie University School of Medicine.
Rinsho Shinkeigaku. 1996 May;36(5):680-2.
We report a case of 44-year-old Japanese man who presented with exercise-induced anaphylaxis. He was admitted to our hospital with chief complaints of repeated episodes of urticaria and nausea induced by exercise. He had allergy to the radiologic contrast iodine material, but no history of atopic dermatitis. Physical and neurological examinations were unremarkable. Treadmill test induced urticaria and nausea in 10 minutes after starting the exercise and the test was discontinued. The systolic blood pressure finally fell down to 51mmHg about 17 minutes after ceasing the exercise, and it returned to normal value with hydrocortisone and noradrenalin injection. Treadmill test increased the serum histamine level, but did not increase serotonin nor IgE levels. Administration of antihistamines and avoidance of hard exercise has protected him from a new attack. We have to pay attention to exercise-induced anaphylaxis as one of the important causes of syncope.
我们报告一例44岁的日本男性，其表现为运动诱发的过敏反应。他因运动诱发反复出现荨麻疹和恶心而入院。他对放射造影碘剂过敏，但无特应性皮炎病史。体格检查和神经系统检查均无异常。跑步机测试在开始运动10分钟后诱发了荨麻疹和恶心，测试中断。运动停止约17分钟后，收缩压最终降至51mmHg，经注射氢化可的松和去甲肾上腺素后恢复正常。跑步机测试使血清组胺水平升高，但未使血清素和IgE水平升高。给予抗组胺药并避免剧烈运动使他免受新的发作。我们必须注意运动诱发的过敏反应，将其作为晕厥的重要原因之一。
