Petrikovsky B M, Schneider E P, Klein V R, Wyse L J, Lesser M
Department of Obstetrics and Gynecology, North Shore University Hospital, Cornell University Medical College, Manhasset, New York 11030, USA.
J Clin Ultrasound. 1996 Nov-Dec;24(9):507-11. doi: 10.1002/(SICI)1097-0096(199611/12)24:9<507::AID-JCU3>3.0.CO;2-R.
To assess the validity of fetal breast size measurement as a sonographic marker in fetuses with Down syndrome.
Fetal breasts were studied in 26 fetuses with trisomy 21 and 78 fetuses with normal chromosomes. Breasts were identified and measured in a cross-sectional plane of the fetal chest at the level of the four-chamber view of the heart. Normal fetuses had a mean breast size of 3.8 mm +/- 1.1 mm. Fetuses with Down syndrome had a mean breast size of 1.9 mm +/- 0.7 mm (p < or = 0.0001). Diminished breast size measured by ultrasound in the second trimester may be helpful in identifying fetuses with Down syndrome.
评估胎儿乳房大小测量作为唐氏综合征胎儿超声标志物的有效性。
对26例21三体胎儿和78例染色体正常的胎儿的乳房进行研究。在胎儿胸部心脏四腔心切面水平的横断面中识别并测量乳房。正常胎儿的平均乳房大小为3.8毫米±1.1毫米。唐氏综合征胎儿的平均乳房大小为1.9毫米±0.7毫米(p≤0.0001)。孕中期超声测量的乳房尺寸减小可能有助于识别唐氏综合征胎儿。