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小儿股骨骨折的血流动力学意义。

Hemodynamic significance of pediatric femur fractures.

作者信息

Lynch J M, Gardner M J, Gains B

机构信息

Department of Pediatric Surgery, Children's Hospital of Pittsburgh, PA 15213-2583, USA.

出版信息

J Pediatr Surg. 1996 Oct;31(10):1358-61. doi: 10.1016/s0022-3468(96)90827-1.

Abstract

PURPOSE

To determine whether hemodynamically significant bleeding occurs after pediatric femur fractures.

METHOD

A retrospective chart review was performed; demographic and injury data were collected for all patients with the diagnosis of femur fracture over a 30-month period at a level/ pediatric trauma center. Included were patients with multisystem injury and patients with femur fractures as the only injury. The incidence of hemodynamic insufficiency, the reasons for and timing of transfusions, and the changes in hematocrit levels over time were evaluated.

RESULTS

One hundred seventy-eight children were identified (182 femur fractures). There were 116 boys and 62 girls, and the mean age was 6.04 +/- 4.5 years (range, 1 month to 19 years). The mechanisms of injury included falls (46), pedestrian/ motor vehicle accidents (43), motor vehicle crashes (19), sports accidents (22), abuse (10), and miscellaneous (38). The mean Injury Severity Score (ISS) was 5.88 +/- 3.93 (range, 4 to 29). There were no deaths. The length of hospital stay was 8.13 +/- 9.37 days (range, 1 to 43 days). Prehospital treatment included early immobilization. Fracture treatment was according to recognized orthopedic techniques based on age, size, and fracture configuration. The mean hematocrit in the emergency department was 34% +/- 3.5% (range, 27.8% to 44.4%) and 32% +/- 6.6% (range, 16.9% to 47.8%) at 24 hours. 67 patients (38%) suffered multiple injuries. Mean ISS for this group was 9.4 +/- 5.0 (range, 5 to 29). Four patients had hemodynamic insufficiency at the time of admission. All were in the multiple-injury group Seven of these 67 patients (10%) required transfusion-three in the first 24 hours (two in the emergency department [associated with severe facial/scalp bleeding] and one in the operating room [associated with severe liver injury]) and four after the first 24 hours (three associated with intraoperative orthopedic procedures and one with a hemothorax). The mean age of those who underwent transfusion was 8.29 +/- 4.79 years, and their mean ISS was 13.71 +/- 4.61. All patients who required transfusion had been injured in motor vehicle crashes or in pedestrian/motor vehicle accidents. One hundred eleven children had isolated closed femur fractures. No patient in this group had evidence of hemodynamic insufficiency or required transfusion. The initial mean hematocrit was 34.5% +/- 2.7%, and the mean 24-hour hematocrit was 34.6% +/- 3.2%. We found that (1) no child with an isolated closed femur fracture had evidence of hemodynamic instability, or showed significant blood loss as evidenced by a decreasing hematocrit at 24 hours, and (2) in this series, evidence of hemodynamic insufficiency and/or the need for transfusion was found only in multiply injured children.

CONCLUSION

Hemodynamic instability or evidence of a declining hematocrit in the child should not be attributed to a closed femur fracture and that other sources of blood loss must be found.

摘要

目的

确定小儿股骨骨折后是否会发生具有血流动力学意义的出血。

方法

进行了一项回顾性病历审查;收集了一家一级小儿创伤中心30个月内所有诊断为股骨骨折患者的人口统计学和损伤数据。纳入的患者包括多系统损伤患者和仅股骨骨折的患者。评估了血流动力学不足的发生率、输血的原因和时间以及血细胞比容水平随时间的变化。

结果

共识别出178名儿童(182处股骨骨折)。其中男孩116名,女孩62名,平均年龄为6.04±4.5岁(范围为1个月至19岁)。损伤机制包括跌倒(46例)、行人/机动车事故(43例)、机动车碰撞(19例)、运动事故(22例)、虐待(10例)和其他(38例)。平均损伤严重度评分(ISS)为5.88±3.93(范围为4至29)。无死亡病例。住院时间为8.13±9.37天(范围为1至43天)。院前治疗包括早期固定。骨折治疗根据公认的骨科技术,依据年龄、体型和骨折形态进行。急诊科的平均血细胞比容为34%±3.5%(范围为27.8%至44.4%),24小时时为32%±6.6%(范围为16.9%至47.8%)。67例患者(38%)为多发伤。该组的平均ISS为9.4±5.0(范围为5至29)。4例患者入院时存在血流动力学不足。均在多发伤组。这67例患者中有7例(10%)需要输血——3例在最初24小时内(2例在急诊科[与严重面部/头皮出血有关],1例在手术室[与严重肝损伤有关]),4例在最初24小时后(3例与术中骨科手术有关,1例与血胸有关)。接受输血患者的平均年龄为8.29±4.79岁,平均ISS为13.71±4.61。所有需要输血的患者均因机动车碰撞或行人/机动车事故受伤。111名儿童为单纯闭合性股骨骨折。该组中无患者有血流动力学不足的证据或需要输血。初始平均血细胞比容为34.5%±2.7%,24小时平均血细胞比容为34.6%±3.2%。我们发现:(1)没有单纯闭合性股骨骨折的儿童有血流动力学不稳定的证据,或在24小时时血细胞比容下降表明有明显失血;(2)在本系列研究中,仅在多发伤儿童中发现血流动力学不足和/或输血需求的证据出现。

结论

儿童血流动力学不稳定或血细胞比容下降的证据不应归因于闭合性股骨骨折,必须寻找其他失血来源。

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