局部心肌缺血对左心室等容收缩的影响。
Effect of regional myocardial ischaemia on left ventricular isovolumic contraction.
作者信息
Goodyer A V, Wong B Y, Langou R
出版信息
Cardiovasc Res. 1977 Jul;11(4):299-309. doi: 10.1093/cvr/11.4.299.
PMID:890708
Abstract
In anaesthetised, open-chest dogs, global isovolumic contractility indices were reduced by acute regional ischaemia involving 12 to 14% or more of left ventricular mass. These effects were not altered by controlled reduction of blood flow to the non-ischaemic region, but were exaggerated by isoprenaline during normal perfusion of the non-ischaemic region. The results were consistent with a contraction model characterised by simple reduction of the effective length of the contractile elements.
摘要
在麻醉开胸犬中，累及左心室质量12%至14%或更多的急性局部缺血会降低整体等容收缩性指标。这些效应不会因对非缺血区域进行可控的血流减少而改变，但在非缺血区域正常灌注期间会被异丙肾上腺素放大。结果与以收缩元件有效长度简单缩短为特征的收缩模型一致。
相似文献
1
Effect of regional myocardial ischaemia on left ventricular isovolumic contraction.局部心肌缺血对左心室等容收缩的影响。
Cardiovasc Res. 1977 Jul;11(4):299-309. doi: 10.1093/cvr/11.4.299.
2
Propranolol and vagal nerve stimulation do not affect postsystolic shortening during acute myocardial ischaemia in the dog.普萘洛尔和迷走神经刺激对犬急性心肌缺血时收缩期后缩短无影响。
Cardiovasc Res. 1988 Aug;22(8):527-36. doi: 10.1093/cvr/22.8.527.
3
Effect of global vs regional ischaemia upon myocardial contractility and oxygen balance.整体缺血与局部缺血对心肌收缩力和氧平衡的影响。
Cardiovasc Res. 1985 Oct;19(10):606-12. doi: 10.1093/cvr/19.10.606.
4
5
The effects of propranolol and acebutolol on left ventricular function and coronary haemodynamics in the conscious dog with myocardial ischaemia.心得安和美托洛尔对清醒心肌缺血犬左心室功能及冠状动脉血流动力学的影响。
Br J Pharmacol. 1980 Mar;68(3):373-9. doi: 10.1111/j.1476-5381.1980.tb14550.x.
6
Reflex hypotension due to regional activation of left ventricular mechanoreceptors to explain the hypotension noted in clinical myocardial ischaemia or reperfusion.由于左心室机械感受器的局部激活导致的反射性低血压，以解释临床心肌缺血或再灌注中出现的低血压。
Cardiovasc Res. 1986 Mar;20(3):161-70. doi: 10.1093/cvr/20.3.161.
7
Alterations of coronary vascular responses to noradrenaline, acetylcholine and isoprenaline during acute myocardial ischaemia in dogs.犬急性心肌缺血期间冠状动脉对去甲肾上腺素、乙酰胆碱和异丙肾上腺素反应的改变
Br J Pharmacol. 1989 Jun;97(2):626-30. doi: 10.1111/j.1476-5381.1989.tb11995.x.
8
Depressed contractile function in reperfused canine myocardium: metabolism and response to pharmacological agents.
Cardiovasc Res. 1980 Aug;14(8):458-68. doi: 10.1093/cvr/14.8.458.
9
Effect of propranolol on regional myocardial function in anesthetized open-chest dogs with myocardial ischemia.
Acta Med Okayama. 1978 Jul;32(3):225-37.
10
Effects of isoproterenol on regional myocardial function, electrogram, and blood flow in conscious dogs with myocardial ischemia.异丙肾上腺素对清醒心肌缺血犬局部心肌功能、心电图及血流的影响。
J Clin Invest. 1976 May;57(5):1261-71. doi: 10.1172/JCI108394.
Zotero 插件